Authors: Milosavić, Nenad, Prodanović, Radivoje, Jankov, Ratko M.

Venue: Tetrahedron Letters

Type: Publication

Abstract: 4-Hydroxyphenyl-beta-isomaltoside has been synthesized by alpha-glucosidase assisted transglycosylation between arbutin as acceptor and sucrose as donor molecules, respectively. Optimum conditions for the transglucosylation reaction were 40 degrees C for 20 h with 10 mM arbutin and 1.5 M sucrose in a 100 mM sodium citrate/phosphate buffer at pH 5.0. The new glucoside was obtained in a 50% molar yield with respect to arbutin. (C) 2007 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.tetlet.2007.07.152