BIP! Finder - The organic esterO,O’-diethyl-(S,S)-ethylenediamine-N,N’-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis

2018 • The organic esterO,O’-diethyl-(S,S)-ethylenediamine-N,N’-di-2-(3-cyclohexyl)propanoate dihydrochloride attenuates murine breast cancer growth and metastasis

Authors: Jurisevic, M., Arsenijevic, A., Pantic, J., Gajovic, N., Milovanovic, Poljarević, Jelena, Sabo, Tibor, Vojvodic, D., Radosavljevic, G.D.

Venue: Oncotarget

Type: Publication

Abstract: Pharmacological treatment of cancer is mostly limited by drug-toxicity and resistance. It has been noticed that new organic ester ligand, O,O'-diethyl-(S,S)- ethylenediamine-N,N'-di-2-(3-cyclohexyl)propanoate dihydrochloride (named DEEDCP) showed effective cytotoxic capacities against several human and mouse cancer cell lines. However, its effects on tumor growth and metastasis are unexplored. The aim of present study was to examine the ability of DE-EDCP to inhibit 4T1 murine breast cancer growth and progression and to explore possible molecul... (read more)

Topics: Internal medicine Oncology Cancer research

DOI: 10.18632/oncotarget.25610

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External links: Crossref OpenAIRE

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