Abstract: Abstract Background Autism, a highly heritable psychiatric condition, is hypothesised believed to be associated with altered synaptic structure and function, as indicated by findings from genetic, post-mortem, and pre-clinical studies. Aims & Objectives In this study, we used positron emission tomography (PET) to investigate synaptic density in vivo. Utilizing a twin design, our objective was to isolate autism specific variation. Methods We examined seven twin pairs discordant for autism (aged 22-29; three male, two female, and two mixex pa...
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