BIP! Finder - In vitro study of iron coordination properties, anti-inflammatory potential, and cytotoxic effects of N-salicylidene and N-vanillidene anil Schiff bases

2018 • In vitro study of iron coordination properties, anti-inflammatory potential, and cytotoxic effects of N-salicylidene and N-vanillidene anil Schiff bases

Authors: Petrović, Zorica D., Đorović, Jelena, Simijonović, Dušica, Trifunović, Snežana S., Vladimir P.

Venue: Chemical Papers

Type: Publication

Abstract: N-Salicylidene and N-vanillidene anil Schiff bases SB-1-5 were evaluated for their iron-coordinating properties. For this purpose, reactions with Fe(III) chloride were performed. The obtained results showed that salicylaldehyde bases SB-1 and SB-2 are the best coordinating ligands among the investigated SBs. The corresponding complexes are obtained in good yield and investigated using UV-Vis spectrophotometry and IR spectroscopy. The inhibitory potential of SB-1-5 against iron-containing enzyme lipoxygenase (LOX) was also tested. Salicylidene b... (read more)

Topics: Stereochemistry Medicinal chemistry Nuclear chemistry

DOI: 10.1007/s11696-018-0419-5

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External links: Crossref OpenAIRE

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