BIP! Finder - MiR-375 and miR-21 as Potential Biomarkers of Prostate Cancer: Comparison of Matching Samples of Plasma and Exosomes

2022 • MiR-375 and miR-21 as Potential Biomarkers of Prostate Cancer: Comparison of Matching Samples of Plasma and Exosomes

Authors: Suzana Matijašević Joković, Zorana Dobrijević, Nevena Kotarac, Lidija Filipović, Milica Popović, Aleksandra Korać, Ivan Vuković, Dušanka Savić-Pavićević, Goran Brajušković

Venue: Genes

Type: Publication

Abstract: MiR-21 and miR-375 have been reported as dysregulated in prostate cancer (PCa) in multiple previous studies. Still, variable or even opposing data for the expression of these microRNAs in PCa were found, and their potential biomarker properties remain elusive. In an attempt to clarify their significance as PCa biomarkers, as well as to compare different types of specimens as a source of relevant microRNAs, we used plasma and matching plasma-derived exosomes from patients with PCa and patients with benign prostatic hyperplasia (BPH). Plasma and ... (read more)

Topics: Internal medicine Oncology

DOI: 10.3390/genes13122320

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External links: Crossref OpenAIRE

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